MIME-Version: 1.0 Content-Type: multipart/related; boundary="----=_NextPart_01C5090B.98F37730" This document is a Single File Web Page, also known as a Web Archive file. If you are seeing this message, your browser or editor doesn't support Web Archive files. Please download a browser that supports Web Archive, such as Microsoft Internet Explorer. ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="us-ascii" Calculating Drug Dosages

Calculating Drug Dosages

 

Calculating Doses from Prepared-Strength Liquids, Tablets, and Capsules

&nbs= p;

Calculating With Proportions

 

Steps:

1.&= nbsp; Convert to a consistent unit of measure.

2.&= nbsp; Set up a proportion:

 

Original dose =3D Desired dose

Per amount       Pe= r amount

 

3.  Cross-multiply= and solve for the unknown (x).

 

Example 1: Tablets

 

How many tablets are needed to deliver 500 mg of Tylenol?<= /o:p>

 

Original dose =3D 250 mg<= /span>

Per amount =3D 1 tablet

 

Desired dose =3D 500 mg

Per amount =3D unknown (x)

 

1.&= nbsp; Set up a proportion:

 

250 mg =3D 500 mg

1 tab          x ta= b

 

2.&= nbsp; Cross-multiply and solve for the unknown (x):

 

250x =3D 500

 

x =3D 500/250 =3D 2

 

Answer: 2 tablets are needed to deli= ver 500 mg of Tylenol

 

 

Example 2: Solutions

 

How many milliliters of elixir are n= eeded to deliver 15 mg of Phenobarbital?

 

Original dose =3D 120 mg<= /span>

Per amount =3D 30 ml

 

Desired dose =3D 15 mg

Per amount =3D x ml

 

1.&= nbsp; Set up a proportion:

 

120 mg =3D 15 mg

&nb= sp; 30 ml     =   x ml

 

2.&= nbsp; Cross-multiply and solve for the unknown (x):

 

120x =3D 450

 

x =3D 450/120 =3D 3.75 ml=

 

Answer: 3.75 ml are needed to delive= r 15 mg of the elixir

 

 

 

I.&n= bsp;            = ;       Drug Amounts in Units<= /span>

 

Some drugs are manufactured in units (U) rather than in gram= s or milligrams.  Note: A unit does= not have a standard metric equivalent. The metric equivalent (milligrams, etc.) varies for each drug. Examples are penicillin, insulin and heparin.  Solving dose problems for these dr= ugs is exactly the same as for other dosage units except that = unit (U) is substituted for milligrams (mg).

 

Example 3: Units

 

How many milliliters are needed to deliver 500 U of heparin?=

 

Original dose =3D 1000U

Per amount =3D 1 ml

 

Desired dose =3D 500 U=

Per amount =3D x ml

 

1.  Set up a proportion:

 

1000 U =3D 500 U

 1 ml         x ml<= /o:p>

 

2.  Cross-multiply and solve for the unknown (x):

&= nbsp;

1000x =3D 500

 

x =3D 500/1000 =3D 0.5 ml

 

Answer: 0.5 ml are needed to deli= ver 500 units of heparin

&= nbsp;

 

II.&= nbsp;           &nbs= p;     Calculations With a Dosage Schedu= le

 

 

There are times when the dose of a drug must be obtained fro= m a schedule, which may be based on the size of the person.  The dose may be presented in mg/kg= of body weight.  This means that = the dose must first be calculated after the body weight is obtained, and then t= he amount of the drug preparation needed can be calculated.<= /p>

&= nbsp;

Steps:

1.      Calculate the dose needed

2.      Convert to a consistent unit of m= easure

3.      Set up a proportion

 

Original dose =3D Desired dose

Per amount       Per amount

 

4.  Cross-multi= ply and solve for the unknown (x)

 

Example 4: Dosage Schedule

 

Using a dosage schedule of 0.1 mg/kg for albuterol syrup, an= d a prepared-strength mixture of 2mg / 5 ml, how much of the syrup is needed fo= r a 30 kg child?

 

1.      Calculate the dose needed:

Dose =3D 0.1 mg/kg x 20 kg =3D 3.0 mg

 

2.      Set up a proportion:

 

Original dose =3D 2.0 mg

Per amount =3D 5 ml

 

Desired dose =3D 3.0 mg

Per amount =3D x ml

 

3.  Set up a proportion, cross-multiply and solve for the unknown (x):

 

2.0 mg =3D 3.0 mg

5 ml         x ml

 

2x =3D 15

 

x =3D 7.5

 

Answer: 7.5 ml are needed to deli= ver 3.0 mg of albuterol syrup to this child

&= nbsp;

&= nbsp;

III.=             &nb= sp;   Calculating Doses From Percentage-Strength Solutions

&= nbsp;

a.      Terms:

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;           i.   &nb= sp;  Solute – the active ingredient (solid or liquid)

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;         ii.   &n= bsp;  Solvent – the liquid that dissolves the solute (sterile H2O, NS)

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;       iii.   &= nbsp;  Solution – a solute which is dissolved in a solvent

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;       iv.   &n= bsp;  Strength – the percentage of solute to total solvent and solute

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;         v.   &nb= sp;  Percentage – parts of the active ingredient (solute) in a preparations contained= in 100 parts of the total preparation (solute and solvent)

b.      Types of Percentage Preparations:=

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;           i.   &nb= sp;  Weight to Weight: Percent in weight (W/W) expresses the number of grams of a drug = or active ingredient in 100 ml of a mixture:

1.      W/W: Grams per 100 g of mixture

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;         ii.   &n= bsp;  Weight to Volume (most common): Percent may be expressed for the number of grams o= f a drug or active ingredient in 100 ml of a mixture:

1.      W/V: Grams per 100 ml of mixture<= o:p>

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;       iii.   &= nbsp;  Volume to Volume: Percent expresses the number of milliliters of drug or active ingredient in 100 ml of a mixture:

1.      V/V: Milliliters per 100 ml of a mixture

c.      Calculating with Percent-Strength Solutions

 

Steps:

1.      Convert the percent solution to m= etric units (mg/1ml)

 

Useful Trick: Percent Solutions can be quickly converted to milligrams per 1 milliliter by moving the decimal one place to the right:

 

Example: 2% solution, move the decimal one place to the righ= t,

2.0. mg/1 = ml =3D 20 mg/1 ml

&= nbsp;

2.      Set up a proportion and substitut= e knowns

 

Original dose =3D Desired dose

Per amount         Per amount

 

1.      Cross-multiply and solve for the unknown (x)

2.      Express answer in the units reque= sted

 

Example 5: Percent-Strength Solution

&= nbsp;

How many milligrams of active ingredient are in 3 ml of a 0.= 083% of albuterol (unit dose)?

 

1.       Convert to metric units (mg/1 ml):<= o:p>

 

0.083% =3D 0.083 g =3D 83 mg =3D 0.83 mg

    &nbs= p;            &= nbsp;      100 ml     100 ml       1 ml=

 

2.  Set up a proportion:

 

    &nbs= p;       0.83 mg =3D     x 

    &nbs= p;        1 ml         3 ml

 

3.  Cross-multi= ply and solve for the unknown (x):

&= nbsp;

x =3D 0.83 * 3

 

x =3D 2.49 mg

 

Answer: There are 2.5 mg of active ingredient in a unit dose= of albuterol.

 

a.      Solutions By Ratio

<= span style=3D'font-family:Arial;mso-fareast-font-family:Arial;color:#003366'>&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;           i.   &nb= sp;  Frequently when diluting a medication for use in an aerosol treatment, a solute to sol= vent ratio is given (1:200, 1:1000)

 

Example 5: Solutions by Ratio

 

How many milligrams of active ingredient are in 2 ml of a 1:= 200 solution of isoproterenol?

 

 1.  Convert to metric units (mg/1 ml):=

a.      Convert to % solution<= /span>

&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;         i.   &nb= sp;  1:200 =3D 1/200 =3D 0.005 x 100 =3D 0.5%

b.      Then, convert to metric units (mg= /1 ml)

&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;         i.   &nb= sp;  0.5% =3D 0.5 g   =3D 500 mg =3D 5 mg

    &nbs= p;               =             &nb= sp;        100 ml   100 ml     1 ml<= /span>

2.  Alternate m= ethod to convert to metric units (mg/1 ml)

    &nbs= p;       a.  1:200= =3D 1 g/200 ml =3D 1000 mg/200 ml =3D 10 mg/2ml =3D 5 mg/1ml

 

3.  Set up a proportion:

 

    &nbs= p;       5 mg =3D     x 

    &nbs= p;       1 ml       2 ml

 

4.  Cross-multi= ply and solve for the unknown (x):

&= nbsp;

x =3D 5 * 2

 

x =3D 10 mg

 

Answer: There are 10 mg of active ingredient in a 1:200 solu= tion of isoproterenol.

 

 

IV.&= nbsp;           &nbs= p;  Solving Dilutions With a Dilute S= olute

 

a.      When the active ingredient, or so= lute is already diluted and less than pure, the following equation is used:=

 

C1 * V1 =3D C2 * V2

 

Solving for V2:

 

V2 =3D C1 * V1 / C2        =             &nb= sp;            =             &nb= sp;            =             &nb= sp;            =             &nb= sp;            =         C2<= /span>

   &nbs= p;           

Where:

    &nbs= p;       C1 =3D desired concentration (in decimals)

    &nbs= p;       V1 =3D desired total volume (mL)=

    &nbs= p;       C2 =3D concentration of solution on hand

    &nbs= p;       V2 =3D volume of solution needed for dilution

 

Steps:

1.      Substitute known variables:<= /o:p>

a.      Concentration of the solution as a decimal

&nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;           &nbs= p;            &= nbsp;         i.   &nb= sp;  20% solution =3D 20/100 =3D 0.20

b.      Volume (ml)

2.      Solve for the unknown variable (V= 2)

3.      Determine the amount of diluent (= normal saline, sterile H2O) needed

a.      Total solution amount – V2

 

Example: Dilutions with a Dilute = Solute

 

How much 20% Mucomyst is needed to prepare 5 ml of a 10% Mucomyst?

 

1.      Substitute the known variables:

 

C1 =3D 0.10

V1 =3D 5 ml

C2 =3D 0.20

V2 =3D unknown

 

2.  Solve for t= he unknown variable (V2):

 

V2 =3D 0.10 * 5  =3D 0.5 = =3D 2.5 ml

    &nbs= p;             0.20       0.2<= o:p>

 

3.  Determine t= he amount of diluent needed:

 

     Total solution amount – V2 =3D amount of diluent ne= eded

 

    &nb= sp; 5 ml – 2.5 ml =3D 2.5 ml diluent

 

Answer: 2.5 ml of 20% Mucomyst and 2.5 ml normal saline are mixed to prepare 5 ml of a 10% solution of Mucomyst

    

 

***Note: S= tudents are not responsible for calculating intravenous infusion rates.<= /span>

    &nbs= p;      

 

 

 

 

 

 

 

 

 

 

------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image002.jpg Content-Transfer-Encoding: base64 Content-Type: image/jpeg /9j/4AAQSkZJRgABAQEAYABgAAD/2wBDAAoHBwgHBgoICAgLCgoLDhgQDg0NDh0VFhEYIx8lJCIf IiEmKzcvJik0KSEiMEExNDk7Pj4+JS5ESUM8SDc9Pjv/2wBDAQoLCw4NDhwQEBw7KCIoOzs7Ozs7 Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozv/wAARCAAIBGMDASIA AhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQA AAF9AQIDAAQRBRIhMUEGE1FhByJxFDKBkaEII0KxwRVS0fAkM2JyggkKFhcYGRolJicoKSo0NTY3 ODk6Q0RFRkdISUpTVFVWV1hZWmNkZWZnaGlqc3R1dnd4eXqDhIWGh4iJipKTlJWWl5iZmqKjpKWm p6ipqrKztLW2t7i5usLDxMXGx8jJytLT1NXW19jZ2uHi4+Tl5ufo6erx8vP09fb3+Pn6/8QAHwEA AwEBAQEBAQEBAQAAAAAAAAECAwQFBgcICQoL/8QAtREAAgECBAQDBAcFBAQAAQJ3AAECAxEEBSEx BhJBUQdhcRMiMoEIFEKRobHBCSMzUvAVYnLRChYkNOEl8RcYGRomJygpKjU2Nzg5OkNERUZHSElK U1RVVldYWVpjZGVmZ2hpanN0dXZ3eHl6goOEhYaHiImKkpOUlZaXmJmaoqOkpaanqKmqsrO0tba3 uLm6wsPExcbHyMnK0tPU1dbX2Nna4uPk5ebn6Onq8vP09fb3+Pn6/9oADAMBAAIRAxEAPwDnPt/g /wD56a1+a0fb/B//AD01r81oor9B/sqh3f3k/Xq/8wfb/B//AD01r81o+3+D/wDnprX5rRRR/ZVD u/vD69X/AJg+3+D/APnprX5rR9v8H/8APTWvzWiij+yqHd/eH16v/MH2/wAH/wDPTWvzWj7f4P8A +emtfmtFFH9lUO7+8Pr1f+YPt/g//nprX5rR9v8AB/8Az01r81ooo/sqh3f3h9er/wAwfb/B/wDz 01r81o+3+D/+emtfmtFFH9lUO7+8Pr1f+YPt/g//AJ6a1+a0fb/B/wDz01r81ooo/sqh3f3h9er/ AMwfb/B//PTWvzWj7f4P/wCemtfmtFFH9lUO7+8Pr1f+YPt/g/8A56a1+a0fb/B//PTWvzWiij+y qHd/eH16v/MH2/wf/wA9Na/NaPt/g/8A56a1+a0UUf2VQ7v7w+vV/wCYPt/g/wD56a1+a0fb/B// AD01r81ooo/sqh3f3h9er/zB9v8AB/8Az01r81o+3+D/APnprX5rRRR/ZVDu/vD69X/mD7f4P/56 a1+a0fb/AAf/AM9Na/NaKKP7Kod394fXq/8AMH2/wf8A89Na/NaPt/g//nprX5rRRR/ZVDu/vD69 X/mD7f4P/wCemtfmtH2/wf8A89Na/NaKKP7Kod394fXq/wDMH2/wf/z01r81o+3+D/8AnprX5rRR R/ZVDu/vD69X/mD7f4P/AOemtfmtH2/wf/z01r81ooo/sqh3f3h9er/zB9v8H/8APTWvzWj7f4P/ AOemtfmtFFH9lUO7+8Pr1f8AmD7f4P8A+emtfmtH2/wf/wA9Na/NaKKP7Kod394fXq/8wfb/AAf/ AM9Na/NaPt/g/wD56a1+a0UUf2VQ7v7w+vV/5g+3+D/+emtfmtH2/wAH/wDPTWvzWiij+yqHd/eH 16v/ADB9v8H/APPTWvzWj7f4P/56a1+a0UUf2VQ7v7w+vV/5hPt/g/8A56a1+a0v2/wf/wA9Na/N aKKP7Kod394fXq/8wfb/AAf/AM9Na/NaPt/g/wD56a1+a0UUf2VQ7v7w+vV/5g+3+D/+emtfmtH2 /wAH/wDPTWvzWiij+yqHd/eH16v/ADB9v8H/APPTWvzWj7f4P/56a1+a0UUf2VQ7v7w+vV/5g+3+ D/8AnprX5rR9v8H/APPTWvzWiij+yqHd/eH16v8AzB9v8H/89Na/NaPt/g//AJ6a1+a0UUf2VQ7v 7w+vV/5g+3+D/wDnprX5rR9v8H/89Na/NaKKP7Kod394fXq/8wfb/B//AD01r81o+3+D/wDnprX5 rRRR/ZVDu/vD69X/AJg+3+D/APnprX5rR9v8H/8APTWvzWiij+yqHd/eH16v/MH2/wAH/wDPTWvz Wj7f4P8A+emtfmtFFH9lUO7+8Pr1f+YPt/g//nprX5rR9v8AB/8Az01r81ooo/sqh3f3h9er/wAw fb/B/wDz01r81o+3+D/+emtfmtFFH9lUO7+8Pr1f+YPt/g//AJ6a1+a0fb/B/wDz01r81ooo/sqh 3f3h9er/AMwfb/B//PTWvzWj7f4P/wCemtfmtFFH9lUO7+8Pr1f+YPt/g/8A56a1+a0fb/B//PTW vzWiij+yqHd/eH16v/MH2/wf/wA9Na/NaPt/g/8A56a1+a0UUf2VQ7v7w+vV/wCYPt/g/wD56a1+ a0fb/B//AD01r81ooo/sqh3f3h9er/zB9v8AB/8Az01r81o+3+D/APnprX5rRRR/ZVDu/vD69X/m D7f4P/56a1+a0fb/AAf/AM9Na/NaKKP7Kod394fXq/8AMH2/wf8A89Na/NaPt/g//nprX5rRRR/Z VDu/vD69X/mD7f4P/wCemtfmtH2/wf8A89Na/NaKKP7Kod394fXq/wDMH2/wf/z01r81o+3+D/8A nprX5rRRR/ZVDu/vD69X/mD7f4P/AOemtfmtH2/wf/z01r81ooo/sqh3f3h9er/zB9v8H/8APTWv zWj7f4P/AOemtfmtFFH9lUO7+8Pr1f8AmD7f4P8A+emtfmtH2/wf/wA9Na/NaKKP7Kod394fXq/8 wfb/AAf/AM9Na/NaPt/g/wD56a1+a0UUf2VQ7v7w+vV/5g+3+D/+emtfmtH2/wAH/wDPTWvzWiij +yqHd/eH16v/ADB9v8H/APPTWvzWj7f4P/56a1+a0UUf2VQ7v7w+vV/5g+3+D/8AnprX5rR9v8H/ APPTWvzWiij+yqHd/eH16v8AzB9v8H/89Na/NaPt/g//AJ6a1+a0UUf2VQ7v7w+vV/5g+3+D/wDn prX5rR9v8H/89Na/NaKKP7Kod394fXq/8wfb/B//AD01r81o+3+D/wDnprX5rRRR/ZVDu/vD69X/ AJg+3+D/APnprX5rR9v8H/8APTWvzWiij+yqHd/eH16v/MH2/wAH/wDPTWvzWj7f4P8A+emtfmtF FH9lUO7+8Pr1f+YPt/g//nprX5rR9v8AB/8Az01r81ooo/sqh3f3h9er/wAwfb/B/wDz01r81o+3 +D/+emtfmtFFH9lUO7+8Pr1f+YPt/g//AJ6a1+a0fb/B/wDz01r81ooo/sqh3f3h9er/AMwfb/B/ /PTWvzWj7f4P/wCemtfmtFFH9lUO7+8Pr1f+YPt/g/8A56a1+a0fb/B//PTWvzWiij+yqHd/eH16 v/MH2/wf/wA9Na/NaPt/g/8A56a1+a0UUf2VQ7v7w+vV/wCYPt/g/wD56a1+a0fb/B//AD01r81o oo/sqh3f3h9er/zB9v8AB/8Az01r81o+3+D/APnprX5rRRR/ZVDu/vD69X/mD7f4P/56a1+a0fb/ AAf/AM9Na/NaKKP7Kod394fXq/8AMH2/wf8A89Na/NaPt/g//nprX5rRRR/ZVDu/vD69X/mD7f4P /wCemtfmtH2/wf8A89Na/NaKKP7Kod394fXq/wDMH2/wf/z01r81o+3+D/8AnprX5rRRR/ZVDu/v D69X/mD7f4P/AOemtfmtH2/wf/z01r81ooo/sqh3f3h9er/zB9v8H/8APTWvzWj7f4P/AOemtfmt FFH9lUO7+8Pr1f8AmE+3+D/+emtfmtFFFH9lUO7+8Pr1f+Y//9k= ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image006.jpg Content-Transfer-Encoding: base64 Content-Type: image/jpeg /9j/4AAQSkZJRgABAQEAYABgAAD/2wBDAAoHBwgHBgoICAgLCgoLDhgQDg0NDh0VFhEYIx8lJCIf IiEmKzcvJik0KSEiMEExNDk7Pj4+JS5ESUM8SDc9Pjv/2wBDAQoLCw4NDhwQEBw7KCIoOzs7Ozs7 Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozs7Ozv/wAARCAAIBGMDASIA AhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQA AAF9AQIDAAQRBRIhMUEGE1FhByJxFDKBkaEII0KxwRVS0fAkM2JyggkKFhcYGRolJicoKSo0NTY3 ODk6Q0RFRkdISUpTVFVWV1hZWmNkZWZnaGlqc3R1dnd4eXqDhIWGh4iJipKTlJWWl5iZmqKjpKWm p6ipqrKztLW2t7i5usLDxMXGx8jJytLT1NXW19jZ2uHi4+Tl5ufo6erx8vP09fb3+Pn6/8QAHwEA AwEBAQEBAQEBAQAAAAAAAAECAwQFBgcICQoL/8QAtREAAgECBAQDBAcFBAQAAQJ3AAECAxEEBSEx BhJBUQdhcRMiMoEIFEKRobHBCSMzUvAVYnLRChYkNOEl8RcYGRomJygpKjU2Nzg5OkNERUZHSElK U1RVVldYWVpjZGVmZ2hpanN0dXZ3eHl6goOEhYaHiImKkpOUlZaXmJmaoqOkpaanqKmqsrO0tba3 uLm6wsPExcbHyMnK0tPU1dbX2Nna4uPk5ebn6Onq8vP09fb3+Pn6/9oADAMBAAIRAxEAPwDnPt/g /wD5661+a0fb/B//AD11r81oor9B/sqh3f3k/Xq/8wfb/B//AD11r81o+3eD/wDnrrX5rRRR/ZVD u/vD69X/AJg+3+D/APnrrX5rR9v8H/8APXWvzWiij+yqHd/eH16v/MH2/wAH/wDPXWvzWj7d4P8A +eutfmtFFH9lUO7+8Pr1f+YPt3g//nrrX5rR9u8H/wDPXWvzWiij+yqHd/eH16v/ADB9u8H/APPX WvzWj7f4P/5661+a0UUf2VQ7v7w+vV/5g+3eD/8AnrrX5rR9v8H/APPXWvzWiij+yqHd/eH16v8A zB9v8H/89da/NaPt/g//AJ661+a0UUf2VQ7v7w+vV/5g+3+D/wDnrrX5rR9u8H/89da/NaKKP7Ko d394fXq/8wfb/B//AD11r81o+3+D/wDnrrX5rRRR/ZVDu/vD69X/AJg+3+D/APnrrX5rR9u8H/8A PXWvzWiij+yqHd/eH16v/MH2/wAH/wDPXWvzWj7f4P8A+eutfmtFFH9lUO7+8Pr1f+YPt/g//nrr X5rR9v8AB/8Az11r81ooo/sqh3f3h9er/wAwfbvB/wDz11r81o+3+D/+eutfmtFFH9lUO7+8Pr1f +YPt/g//AJ661+a0fb/B/wDz11r81ooo/sqh3f3h9er/AMwfbvB//PXWvzWj7f4P/wCeutfmtFFH 9lUO7+8Pr1f+YPt/g/8A5661+a0fb/B//PXWvzWiij+yqHd/eH16v/MH2/wf/wA9da/NaPt3g/8A 5661+a0UUf2VQ7v7w+vV/wCYPt/g/wD5661+a0fb/B//AD11r81ooo/sqh3f3h9er/zB9v8AB/8A z11r81o+3eD/APnrrX5rRRR/ZVDu/vD69X/mD7f4P/5661+a0fb/AAf/AM9da/NaKKP7Kod394fX q/8AMH27wf8A89da/NaPt3g//nrrX5rRRR/ZVDu/vD69X/mD7d4P/wCeutfmtH27wf8A89da/NaK KP7Kod394fXq/wDMH2/wf/z11r81o+3+D/8AnrrX5rRRR/ZVDu/vD69X/mD7f4P/AOeutfmtH27w f/z11r81ooo/sqh3f3h9er/zB9v8H/8APXWvzWj7f4P/AOeutfmtFFH9lUO7+8Pr1f8AmD7f4P8A +eutfmtH27wf/wA9da/NaKKP7Kod394fXq/8wfb/AAf/AM9da/NaPt/g/wD5661+a0UUf2VQ7v7w +vV/5g+3+D/+eutfmtH2/wAH/wDPXWvzWiij+yqHd/eH16v/ADB9u8H/APPXWvzWj7f4P/5661+a 0UUf2VQ7v7w+vV/5g+3+D/8AnrrX5rR9v8H/APPXWvzWiij+yqHd/eH16v8AzB9u8H/89da/NaPt /g//AJ661+a0UUf2VQ7v7w+vV/5g+3+D/wDnrrX5rR9v8H/89da/NaKKP7Kod394fXq/8wfb/B// AD11r81o+3eD/wDnrrX5rRRR/ZVDu/vD69X/AJg+3+D/APnrrX5rR9v8H/8APXWvzWiij+yqHd/e H16v/MH2/wAH/wDPXWvzWj7d4P8A+eutfmtFFH9lUO7+8Pr1f+YPt/g//nrrX5rR9v8AB/8Az11r 81ooo/sqh3f3h9er/wAwfb/B/wDz11r81o+3+D/+eutfmtFFH9lUO7+8Pr1f+YPt3g//AJ661+a0 fbvB/wDz11r81ooo/sqh3f3h9er/AMwfbvB//PXWvzWj7d4P/wCeutfmtFFH9lUO7+8Pr1f+YPt/ g/8A5661+a0fbvB//PXWvzWiij+yqHd/eH16v/MH2/wf/wA9da/NaPt/g/8A5661+a0UUf2VQ7v7 w+vV/wCYPt/g/wD5661+a0fbvB//AD11r81ooo/sqh3f3h9er/zB9v8AB/8Az11r81o+3+D/APnr rX5rRRR/ZVDu/vD69X/mD7f4P/5661+a0fb/AAf/AM9da/NaKKP7Kod394fXq/8AMH27wf8A89da /NaPt/g//nrrX5rRRR/ZVDu/vD69X/mD7f4P/wCeutfmtH2/wf8A89da/NaKKP7Kod394fXq/wDM H27wf/z11r81o+3+D/8AnrrX5rRRR/ZVDu/vD69X/mD7f4P/AOeutfmtH2/wf/z11r81ooo/sqh3 f3h9er/zB9v8H/8APXWvzWj7d4P/AOeutfmtFFH9lUO7+8Pr1f8AmD7f4P8A+eutfmtH2/wf/wA9 da/NaKKP7Kod394fXq/8wfb/AAf/AM9da/NaPt3g/wD5661+a0UUf2VQ7v7w+vV/5g+3+D/+eutf mtH2/wAH/wDPXWvzWiij+yqHd/eH16v/ADB9v8H/APPXWvzWj7f4P/5661+a0UUf2VQ7v7w+vV/5 g+3eD/8AnrrX5rR9v8H/APPXWvzWiij+yqHd/eH16v8AzB9v8H/89da/NaPt/g//AJ661+a0UUf2 VQ7v7w+vV/5g+3eD/wDnrrX5rR9u8H/89da/NaKKP7Kod394fXq/8wfbvB//AD11r81o+3eD/wDn rrX5rRRR/ZVDu/vD69X/AJg+3+D/APnrrX5rR9u8H/8APXWvzWiij+yqHd/eH16v/MH2/wAH/wDP XWvzWj7f4P8A+eutfmtFFH9lUO7+8Pr1f+YPt/g//nrrX5rR9v8AB/8Az11r81ooo/sqh3f3h9er /wAwfbvB/wDz11r81o+3+D/+eutfmtFFH9lUO7+8Pr1f+YPt/g//AJ661+a0fb/B/wDz11r81ooo /sqh3f3h9er/AMwfbvB//PXWvzWj7f4P/wCeutfmtFFH9lUO7+8Pr1f+YPt/g/8A5661+a0fb/B/ /PXWvzWiij+yqHd/eH16v/MH2/wf/wA9da/NaPt3g/8A5661+a0UUf2VQ7v7w+vV/wCYPt/g/wD5 661+a0fb/B//AD11r81ooo/sqh3f3h9er/zB9v8AB/8Az11r81o+3eD/APnrrX5rRRR/ZVDu/vD6 9X/mD7f4P/5661+a0fb/AAf/AM9da/NaKKP7Kod394fXq/8AMH2/wf8A89da/NaPt/g//nrrX5rR RR/ZVDu/vD69X/mD7d4P/wCeutfmtFFFH9lUO7+8Pr1f+Y//2Y== ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image001.jpg Content-Transfer-Encoding: base64 Content-Type: image/jpeg /9j/4AAQSkZJRgABAQEBLAEsAAD/2wBDAAUDBAQEAwUEBAQFBQUGBwwIBwcHBw8LCwkMEQ8SEhEP ERETFhwXExQaFRERGCEYGh0dHx8fExciJCIeJBweHx7/2wBDAQUFBQcGBw4ICA4eFBEUHh4eHh4e Hh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh4eHh7/wAARCAAFAfQDASIA AhEBAxEB/8QAHwAAAQUBAQEBAQEAAAAAAAAAAAECAwQFBgcICQoL/8QAtRAAAgEDAwIEAwUFBAQA AAF9AQIDAAQRBRIhMUEGE1FhByJxFDKBkaEII0KxwRVS0fAkM2JyggkKFhcYGRolJicoKSo0NTY3 ODk6Q0RFRkdISUpTVFVWV1hZWmNkZWZnaGlqc3R1dnd4eXqDhIWGh4iJipKTlJWWl5iZmqKjpKWm p6ipqrKztLW2t7i5usLDxMXGx8jJytLT1NXW19jZ2uHi4+Tl5ufo6erx8vP09fb3+Pn6/8QAHwEA AwEBAQEBAQEBAQAAAAAAAAECAwQFBgcICQoL/8QAtREAAgECBAQDBAcFBAQAAQJ3AAECAxEEBSEx BhJBUQdhcRMiMoEIFEKRobHBCSMzUvAVYnLRChYkNOEl8RcYGRomJygpKjU2Nzg5OkNERUZHSElK U1RVVldYWVpjZGVmZ2hpanN0dXZ3eHl6goOEhYaHiImKkpOUlZaXmJmaoqOkpaanqKmqsrO0tba3 uLm6wsPExcbHyMnK0tPU1dbX2Nna4uPk5ebn6Onq8vP09fb3+Pn6/9oADAMBAAIRAxEAPwDxf/hP bD/on3hv/wADtV/+TaP+E9sP+ifeG/8AwO1X/wCTaKK/q7/VjKv+fK+9/wCZ539r4/8A5/S+9h/w nth/0T7w3/4Har/8m0f8J7Yf9E+8N/8Agdqv/wAm0UUf6sZV/wA+V97/AMw/tfH/APP6X3sP+E9s P+ifeG//AAO1X/5No/4T2w/6J94b/wDA7Vf/AJNooo/1Yyr/AJ8r73/mH9r4/wD5/S+9h/wnth/0 T7w3/wCB2q//ACbR/wAJ7Yf9E+8N/wDgdqv/AMm0UUf6sZV/z5X3v/MP7Xx//P6X3sP+E9sP+ife G/8AwO1X/wCTaP8AhPbD/on3hv8A8DtV/wDk2iij/VjKv+fK+9/5h/a+P/5/S+9h/wAJ7Yf9E+8N /wDgdqv/AMm0f8J7Yf8ARPvDf/gdqv8A8m0UUf6sZV/z5X3v/MP7Xx//AD+l97D/AIT2w/6J94b/ APA7Vf8A5No/4T2w/wCifeG//A7Vf/k2iij/AFYyr/nyvvf+Yf2vj/8An9L72H/Ce2H/AET7w3/4 Har/APJtH/Ce2H/RPvDf/gdqv/ybRRR/qxlX/Plfe/8AMP7Xx/8Az+l97D/hPbD/AKJ94b/8DtV/ +TaP+E9sP+ifeG//AAO1X/5Nooo/1Yyr/nyvvf8AmH9r4/8A5/S+9h/wnth/0T7w3/4Har/8m0f8 J7Yf9E+8N/8Agdqv/wAm0UUf6sZV/wA+V97/AMw/tfH/APP6X3sP+E9sP+ifeG//AAO1X/5No/4T 2w/6J94b/wDA7Vf/AJNooo/1Yyr/AJ8r73/mH9r4/wD5/S+9h/wnth/0T7w3/wCB2q//ACbR/wAJ 7Yf9E+8N/wDgdqv/AMm0UUf6sZV/z5X3v/MP7Xx//P6X3sP+E9sP+ifeG/8AwO1X/wCTaP8AhPbD /on3hv8A8DtV/wDk2iij/VjKv+fK+9/5h/a+P/5/S+9h/wAJ7Yf9E+8N/wDgdqv/AMm0f8J7Yf8A RPvDf/gdqv8A8m0UUf6sZV/z5X3v/MP7Xx//AD+l97D/AIT2w/6J94b/APA7Vf8A5No/4T2w/wCi feG//A7Vf/k2iij/AFYyr/nyvvf+Yf2vj/8An9L72H/Ce2H/AET7w3/4Har/APJtH/Ce2H/RPvDf /gdqv/ybRRR/qxlX/Plfe/8AMP7Xx/8Az+l97D/hPbD/AKJ94b/8DtV/+TaP+E9sP+ifeG//AAO1 X/5Nooo/1Yyr/nyvvf8AmH9r4/8A5/S+9h/wnth/0T7w3/4Har/8m0f8J7Yf9E+8N/8Agdqv/wAm 0UUf6sZV/wA+V97/AMw/tfH/APP6X3sP+E9sP+ifeG//AAO1X/5No/4T2w/6J94b/wDA7Vf/AJNo oo/1Yyr/AJ8r73/mH9r4/wD5/S+9h/wnth/0T7w3/wCB2q//ACbR/wAJ7Yf9E+8N/wDgdqv/AMm0 UUf6sZV/z5X3v/MP7Xx//P6X3sP+E9sP+ifeG/8AwO1X/wCTaP8AhPbD/on3hv8A8DtV/wDk2iij /VjKv+fK+9/5h/a+P/5/S+9h/wAJ7Yf9E+8N/wDgdqv/AMm0f8J7Yf8ARPvDf/gdqv8A8m0UUf6s ZV/z5X3v/MP7Xx//AD+l97D/AIT2w/6J94b/APA7Vf8A5No/4T2w/wCifeG//A7Vf/k2iij/AFYy r/nyvvf+Yf2vj/8An9L72H/Ce2H/AET7w3/4Har/APJtH/Ce2H/RPvDf/gdqv/ybRRR/qxlX/Plf e/8AMP7Xx/8Az+l97D/hPbD/AKJ94b/8DtV/+TaP+E9sP+ifeG//AAO1X/5Nooo/1Yyr/nyvvf8A mH9r4/8A5/S+9h/wnth/0T7w3/4Har/8m0f8J7Yf9E+8N/8Agdqv/wAm0UUf6sZV/wA+V97/AMw/ tfH/APP6X3sP+E9sP+ifeG//AAO1X/5No/4T2w/6J94b/wDA7Vf/AJNooo/1Yyr/AJ8r73/mH9r4 /wD5/S+9h/wnth/0T7w3/wCB2q//ACbR/wAJ7Yf9E+8N/wDgdqv/AMm0UUf6sZV/z5X3v/MP7Xx/ /P6X3sP+E9sP+ifeG/8AwO1X/wCTaP8AhPbD/on3hv8A8DtV/wDk2iij/VjKv+fK+9/5h/a+P/5/ S+9h/wAJ7Yf9E+8N/wDgdqv/AMm0f8J7Yf8ARPvDf/gdqv8A8m0UUf6sZV/z5X3v/MP7Xx//AD+l 97D/AIT2w/6J94b/APA7Vf8A5No/4T2w/wCifeG//A7Vf/k2iij/AFYyr/nyvvf+Yf2vj/8An9L7 2H/Ce2H/AET7w3/4Har/APJtFFFH+rGVf8+V97/zD+18f/z+l97P/9n= ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image003.gif Content-Transfer-Encoding: base64 Content-Type: image/gif R0lGODlhFAAPAHcAMSH+GlNvZnR3YXJlOiBNaWNyb3NvZnQgT2ZmaWNlACH5BAEAAAAALAIAAgAP AAwAgAAAAAAAAAIdBGKpi+sX2mtROlTjxPlqYyUZ9UDfMV3qBobeUwAAOw== ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image004.gif Content-Transfer-Encoding: base64 Content-Type: image/gif R0lGODlhNQAlAHcAMSH+GlNvZnR3YXJlOiBNaWNyb3NvZnQgT2ZmaWNlACH5BAEAAAAALAAAAAAB AAEAgAAAAAECAwICRAEAOw== ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/image005.gif Content-Transfer-Encoding: base64 Content-Type: image/gif R0lGODlhAwAMAHcAMSH+GlNvZnR3YXJlOiBNaWNyb3NvZnQgT2ZmaWNlACH5BAEAAAAALAAAAAAB AAEAgAAAAAECAwICRAEAOw== ------=_NextPart_01C5090B.98F37730 Content-Location: file:///C:/E5622913/CalculatingDrugDosages_files/filelist.xml Content-Transfer-Encoding: quoted-printable Content-Type: text/xml; charset="utf-8" ------=_NextPart_01C5090B.98F37730--